Πλοήγηση ανά Θέμα "protein kinase"
Αποτελέσματα 1-5 από 5
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Genetic and molecular pathogenesis of Parkinson's disease
(2006)Parkinson's disease (PD), a common progressive degenerative disease of the central nervous system, affects about 1% of adults aged older than 60 years. PD is characterized by rigidity, tremor, postural instability and ... -
Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1α
(2006)Hypoxia-inducible factor 1 (HIF-1) controls the expression of most genes induced by hypoxic conditions. Regulation of expression and activity of its inducible subunit, HIF-1α, involves several post-translational modifications. ... -
Inflammaging and Skeletal Muscle: Can Protein Intake Make a Difference?
(2016)Inflammaging is the chronic low-grade inflammatory state present in the elderly, characterized by increased systemic concentrations of proinflammatory cytokines. It has been shown that inflammaging increases the risk of ... -
Molecular Imprinting of Tri-O-Acetyladenosine for the Synthetic Imitation of an ATP-Binding Cleft in Protein Kinases
(2013)A number of diseases, including cancer, diabetes, and inflammation, are linked to deregulation of cell signaling pathways controlled by protein kinases. Inhibition of the kinases involved can interrupt aberrant signaling ... -
Tumor heterogenicity: Multiple needle biopsies from different lesion sites-key to successful targeted therapy and immunotherapy
(2018)[No abstract available]